Depression, a widespread mental health condition affecting over 264 million people globally, requires effective treatment options. While established treatments exist, ongoing research seeks innovative approaches, with CBD emerging as a potential candidate. Unlike cannabis, CBD doesn’t induce a “high” and is derived mainly from legal hemp sources.
CBD and Depression
Numerous anecdotal reports suggest CBD’s efficacy in alleviating depression symptoms. Animal studies hint at its antidepressant-like effects, impacting the endocannabinoid system brain and serotonin receptors associated with mood regulation. Additionally, CBD may stimulate brain-derived neurotrophic factor (BDNF) and possess anti-stress properties, factors potentially linked to depression relief.
CBD & Depression Mayo Clinic: Insights from Studies
Research on CBD anxiety study, notably conducted by reputable institutions like the Mayo Clinic, has predominantly involved lab animals, with a handful of human studies offering promising results. Some notable examples include:
- A 2012 study on cancer patients with chronic pain highlighted an improvement in depression symptoms with CBD and THC.
- Surveys indicate that over 1 in 6 individuals have used CBD for managing depression, with a majority reporting moderate to significant improvement.
- A 2022 study affirmed the positive impact of CBD on both anxiety and depression symptoms in young individuals.
- Thinking if CBD make anxiety worse? Well, you might be wrong. Ongoing studies are revealing positive outcomes regarding CBD’s potential in bipolar disorder and its influence on depression symptoms in cases of chronic pain.
Does CBD Really Help Depression and Anxiety
Research suggests that CBD may offer potential benefits for issues commonly associated with depression, such as anxiety or panic disorder. A 2017 review exploring the effects of CBD on panic disorder revealed positive outcomes. Panic disorder, affecting approximately 5 percent of the global population, is characterized by unexpected and recurring panic attacks.
In human models, a single dose of 300 milligrams (mg) of CBD demonstrated a notable decrease in anxiety levels, particularly evident after a simulated public speaking test, as indicated by one study in the review. Another study found that the administration of 600 mg of CBD led to a significant reduction in anxiety measures among individuals with social anxiety disorder.
Exploring CBD Products
CBD products come in various forms, including oils, edibles, vapes, and topicals. However, when addressing internal conditions like depression, topical applications are generally ineffective. Since human trials are scarce, determining the most effective CBD form remains uncertain. Opting for high-quality products from reputable brands is crucial, regardless of the chosen form.
Finding the Right Balance
Determining the ideal CBD dosage for depression lacks standardized guidelines. Clinical trials often involve high doses, making them impractical for daily use. Starting with 10 to 20 milligrams per day and gradually increasing is a common recommendation. Consulting with a healthcare professional, particularly a CBD-friendly doctor, can provide personalized dosage guidance.
CBD vs. Traditional Treatments
Comparative research between CBD treatment for anxiety and conventional depression treatments is limited. However, potential advantages of CBD include faster onset compared to traditional antidepressants, which may take weeks to produce effects. Additionally, CBD may avoid common antidepressant side effects like increased anxiety, sexual dysfunction, and mood changes.
Risks and Side Effects
The consumption of CBD orally, through inhalation, or topical application generally does not seem to result in adverse effects. However, individuals sensitive to the compounds in CBD may experience:
- Changes in appetite or weight
It’s important to note that CBD can interact with various medications and potentially increase liver toxicity. The FDA-approved CBD product, Epidiolex for anxiety, comes with a warning regarding the risk of liver problems among users. Also, special caution is advised for medications that caution against consuming grapefruit, as CBD may have similar interaction effects.
While there’s promising evidence that CBD might help with anxiety and depression symptoms, it’s important to recognize the current research has its limits. Before you hop on the CBD train, especially if you’re already using antidepressants, it’s smart to chat with a pro. You want to make sure you’re taking care of your mental health in the best way possible, right? So, go have a chat with your doc before making any moves.