A new study of mice from The National Institute on Drug Abuse shows that CBD – the second most active ingredient in cannabis after THC – may be able to help those addicted to cocaine.

It seems that – at least in mice – using CBD to activate the CB2 receptor, which a growing body of evidence suggests resides in the brain, can reduce cocaine consumption.

The study found that JWH133, a synthetic drug that activates the CB2 receptor, reduced intravenous cocaine administration in mice by 50-60%.

“It’s a very significant reduction,” says Zheng-Xiong Xi, the lead author of the study and a researcher at the National Institute on Drug Abuse.

Researchers are excited about these developments since JWH133 doesn’t seem to produce a high, or a negative experience.

But using marijuana to get off of harder drugs is hardly a new phenomenon.

Ethnographic research by Ric Curtis, chair of anthropology at John Jay College in New York suggests that, as is often the case, addicts may have been ahead of the researchers in discovering this potential property of marijuana. National surveys found that as crack use declined in the early 1990′s, marijuana use rose— and Curtis found that many crack users reported deliberately substituting marijuana for crack, seeking a cheaper and less disruptive high.

Almost everyday seems to bring new developments in the medical and science world when it comes to cannabis. And everyday the arguments of those who oppose legalization – of medical marijuana in particular – seems more and more outdated.

- Joe Klare

About The Author

Joe Klare has been writing about marijuana issues for the past 5 years online, in print and on air.

  • Rev. Guido S. DeLuxe

    it’s also interesting that JWH133 is another in the series of compounds discovered by John W. Huffman that has recently been made illegal because of their connection to synthetic marijuana…